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DIR is now evaluating patients to receive treatment for CCSVI (Chronic Cerebrospinal Venous Insufficiency).

We are currently the only center in Ohio offering this treatment.

CCSVI Treatment FAQ

Here are some FAQs (frequently asked questions) about the procedure for CCSVI at Dayton Interventional Radiology:

This is a narrowing of the neck and chest veins draining the brain and upper spinal cord which may contribute to the progression of MS. Studies linking MS and CCSVI are inconclusive. Some studies have suggested a link while others have not. In addition, the criteria used to diagnose CCSVI has not been adequately established.

Overall the procedure is considered safe.  We were participating in a IRB approved study that is closely monitored for any adverse events.  This study is currently temporarily not enrolling patients because of its IDE (Investigational Device Exemption) status that is currently in negotiation with the FDA.  There have been rare occurrences of clot formation at the angioplasty site (3-5%).  The FDA has received report of one patient (not from our center) who died from bleeding in the brain and one patient who suffered paralysis from a stroke.  Other rare events include stent migration (we only use stents when necessary), venous injury, blood clots in a brain vein, cranial nerve damage, and abdominal bleeding.

We can be reached at: 937-424-2580.  Our dedicated staff for CCSVI patients will help facilitate your tests, consultation, and procedure.

Our center is located at 3075 Governor’s Place Blvd Suite #120, Dayton, OH 45409.

Setting up an appointment with us is easy!  Just submit an inquiry to our website at  Once you have submitted your form, one of our CCSVI coordinators will contact you within 24-48 hours to confirm a date and time for your procedure. You may also contact our office at (937) 424-2580 and our CCSVI coordinator will be able to assist you.

No, there is no wait for the procedure.  All patients can have an appointment as early as 7-10 days from contacting our office (based on availability).

Dayton Interventional Radiology is the only CCSVI practice in the country with a Fellowship trained, Board Certified Neuroradiologist and Interventional Radiologist (Dr. Syed) who specializes in the treatment of both central nervous system and venous disorders.  Triple Board Certification in Interventional Radiology(including the endovascular treatment of venous disorders), Neuroradiology (for the diagnosis and treatment or neurologic disorders) and Interventional Pain Medicine (for the treatment of painful conditions).  He has written a book regarding pain procedures.  He has also published several original articles on “cutting edge” treatments.  Also he is very available to talk to patients through his personal cellphone.  Plus, scheduling your appointment with us is easy.  Lastly, only two days of stay is required for the procedure including the day of the procedure if driving (3 days of stay is required if flying).

The consultation is done on the same day as the procedure.  We ask that you stay for one day after the procedure.  This ensures that you are available for any follow-up the day after your procedure.  Thus, most patients will be in Ohio for about 3 days including arrival the day before the procedure.

Dayton Interventional Radiology has a dedicated staff person who can help facilitate all of your travel needs if desired.  You are not obligated to use these services but it is available to you.

Dayton Marriott – 1414 S Patterson Blvd, Dayton, OH

For patients who would like help with ground transportation, we recommend working with Medtrans and Eagle One.  Although you are not obligated to use their service, we feel that it provides a level of service which helps minimize the stress of ground transportation while with us in Ohio.

Continuity of care can have benefits to you and your overall health.  However, if you want to transfer your care to another physician or seek a second opinion at our center, you may contact our office.

Yes.  We have been treating patients from Canada and are open to treating patients from other countries around the world.

We do not require any testing prior to your treatment.  If you wish to have an MRV or doppler ultrasound (Zamboni protocol) done you may schedule it with us the morning of your consultation.

We also encourage you to send a copy of your CD to our office address listed above, Attn: CCSVI Patient Coordinator.

The procedure includes the venographic evaluation of the jugular and azygos veins (Zamboni protocol).  Treatment typically involves venoplasty of the jugular veins and the azygos vein.

No, unless noted otherwise by our physician.

The use of drug-eluding stents and balloons have been in practice for many years for a variety of indications.  However, in CCSVI, the cause of blockages inside the vein is completely different from heart disease and other artery diseases.  The proper treatment of vein blockages in CCSVI is to tear the valve open which causes a permanent fix of the blockage.  The use of drug-eluting devices is contradictory to the etiology of the disease process in CCSVI and is thus, completely useless.

To help prevent blood clots from forming inside of the veins after the procedure, all of our patients are placed on a blood thinner after the procedure if appropriate.  The blood thinner that we use is called Lovenox and will be given to you following your procedure or at the time of your consultation.  There may be an additional cost associated with your Lovenox (please see “Costs” section below).  Lovenox may be offered in coordination with your primary care physician.

Your procedure is performed on an outpatient basis.  This means that you will check-in in the morning, have the procedure, and be allowed to leave our center after the procedure and after you meet our discharge criteria.

We perform all of our procedures at our medical center in Dayton, OH.

The vascular center where we provide CCSVI treatments have been used by our group for many years, specifically for endovascular procedures.  These centers have been designed and built to specialize in venograms, angiograms, angioplasties, and stenting.  Our centers are not required to have a designated accreditation like hospitals so there is no formal ‘certificate’ or ‘accreditation’.

As a private group specializing in a wide range of treatments and diseases, we have active privileges at several area hospitals.  We provide both inpatient and outpatient services at these hospitals on a daily basis.  Of note, we have an experienced fulltime ICU trained nurse and Certified Registered Nurse Anesthetist at our facility.

No formal follow-up testing is required.  It is simply optional.  Canadian patients may participate in the Canadian Doppler Study with Dr. Sandy McDonald for pre and post-procedure follow-up.  Patients will be seen the next day with an ultrasound for followup.  Additional visits and ultrasounds are optional.

At this time we are following patients based on their response to treatment.  Specifically, if a patient improves after the procedure, and then loses those improvements months later, we would discuss your options with you at that time.

Our fee includes ALL costs associated with the procedure.  This does include the hotel stay while in Ohio, the consultation prior to your procedure, the procedure itself, and any follow up visits with our physicians after the procedure.  The procedure includes all nursing, medications, anesthesia, materials (not including stents), recovery time, and facility charges.  The only other cost is for Lovenox, the blood thinner which is required after the procedure.  There are no other hidden costs!

The local pharmacy charges approximately $140.00 USD per day of subcutaneous injections twice daily.  The average time that a patient is on Lovenox is 10 days. Lovenox is FDA approved in the US for the prevention of deep vein thrombosis. Pradaxa is an alternative drug that can be used in place of Lovenox and Coumadin. It is taken orally and costs approximated $300.00 USD for 30 days. This drug has no antidote however should any serious bleeding occur. ***Costs of the medication are subject to change depending on the pharmacy***

No.  The procedure is considered experimental for CCSVI or MS as the indication.

We accept certified checks or all major credit cards as payment for the procedure.  Patients wishing to use a credit card may contact their credit card company to obtain a cash advance for a check.  All payments must be in US Dollars to be accepted by our office.

Yes.  You can withdraw money from your HSA and use that money for a certified check.

We have been involved with CCSVI patients for approximately 3 years.  We are the first group to treat CCSVI patients in Ohio and it’s neighboring states.

Each of the physicians at Dayton Interventional Radiology have been treating central venous occlusive disease for years, long before the discovery of CCSVI.  Our physician has performed thousands of central venograms and angioplasties for blocked veins for a variety of different diseases.  This extensive experience helps allow us to be a leader in the treatment of CCSVI.

Yes.  Our physician is Board Certified in his respective fields (Neuroradiology and Interventional Radiology).  In addition, since Dayton Interventional Radiology specializes in the treatment of pain, he is also Board Certified by the American Society of Interventional Pain Physicians.

Yes.  Our physician has completed a fellowship in Neuroradiology and Interventional Radiology.  Since neuroradiologic and interventional techniques are the ones used in the treatment of CCSVI patients, we feel fellowship training is very important to ensuring expert care for our patients.

Yes.  We perform venograms on both of the jugular veins and the azygos vein to check for any blockages just as Dr. Zamboni did in his study.  We then treat any abnormalities that we find just as Dr. Zamboni has done.

The procedures which we are performing on patients (venogram and angioplasty) have been in use for many decades.  Endovenous angioplasty and stenting are established and safe techniques in their application to the venous obstructions seen in the jugular and azygos veins.  These procedures are therefore not experimental for indications other than CCSVI.  We do not know if treating these types of blockages will have any benefit for patients with MS.  Symptoms such as fatigue, headache, insomnia, impaired cognition and vision, disturbed balance, heat intolerance, numbness, stiffness, tremors, weakness, urinary and bowel disturbances, etc. are often present in patients with blockages of the jugular or azygos veins and may respond to angioplasty.

For more information, please call (937) 424-2580

The FDA has issued a general warning for “potential dangers of unproven treatment for multiple sclerosis” and specifically the procedures related to studies with balloon angioplasty devices or stents. We wanted to forward you the link to the FDA website, below, for awareness.