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DIR is now evaluating patients to receive treatment for CCSVI (Chronic Cerebrospinal Venous Insufficiency).

We are currently the only center in Ohio offering this treatment.

CCSVI Treatment FAQ

Here are some FAQs (frequently asked questions) about the procedure for CCSVI at Dayton Interventional Radiology:

This is a narrowing of the neck and chest veins draining the brain and upper spinal cord which may contribute to the progression of MS. Studies linking MS and CCSVI are inconclusive. Some studies have suggested a link while others have not. In addition, the criteria used to diagnose CCSVI has not been adequately established.

There have been rare occurrences of clot formation at the angioplasty site (3-5%). The FDA has received report of one patient (not from our center) who died from bleeding in the brain and one patient who suffered paralysis from a stroke. Other rare events include venous injury, blood clots in a brain vein, cranial nerve damage, and abdominal bleeding.

We can be reached at: 937-424-2580.  Our dedicated staff for CCSVI patients will help facilitate your tests, consultation, and procedure.

Our center is located at 3075 Governor’s Place Blvd Suite #120, Dayton, OH 45409.

Setting up an appointment with us is easy!  Just submit an inquiry to our website at  Once you have submitted your form, one of our CCSVI coordinators will try to contact you within 48 hours to confirm a date and time for your procedure. You may also contact our office at (937) 424-2580 or our CCSVI coordinator, (937)-389-6979, for scheduling and basic information.

Based on availability, appointments can be scheduled, on average, within 4-8 weeks of your initial request.

Dayton Interventional Radiology is the only CCSVI practice in the country with a Fellowship trained, Board Certified Neuroradiologist and Interventional Radiologist (Dr. Mubin I Syed) who specializes in the treatment of both central nervous system and venous disorders. Has 6 Board Certification in Interventional Radiology, Neuroradiology, Endovascular Medicine and Obesity Medicine and Interventional Pain Medicine. He has written a book regarding pain procedures. He has also published several original articles on “cutting edge” treatments, including bariatric embolization for weight loss surgery and vertebroplasty/kyphoplasty) and has received multiple patents for medical devices and treatments. Also, he is very available to talk to patients through his personal cellphone. Plus, scheduling your appointment with us is easy. Lastly, only 3 days of stay is required for the procedure. We were one of a few centers that worked closely with the FDA from 2012-2013 to successfully develop an FDA-IDE study for CCSVI outcomes and safety.

The consultation is done on the same day as the procedure. We ask that you stay for one day after the procedure. This ensures that you are available for any follow-up the day after your procedure. Thus, most patients will be in Ohio for about 3 days including arrival the day before the procedure. After the follow-up appointment patients are free to leave unless directed otherwise.

Marriott at the University of Dayton (937-223-1000) – 1414 S Patterson Blvd, Dayton, OH, 45409

Our dedicated CCSVI coordinator (can be reached at 937-389-6979), may be able to assist you in coordinating your travel plans to Dayton, Ohio. Unfortunately travel to and from our offices is not included in the services, there is a complimentary hotel shuttle available to you and further information on its availability can be obtained from Marriott at the University of Dayton (937-223-1000). If you require specialized medical transportation, we recommend working with Medtrans (1-800-854-2137) or Eagle One (937-236-5612). Although you are not obligated to use their service, we feel that it provides a level of service which helps minimize the stress of ground transportation while with us in Ohio. Your hotel stay and room expense are included and scheduled by our CCSVI coordinator, please contact them for any special requests or concerns you may have regarding your reservation.

Yes, we have treated many patients successfully from other physicians who have previously performed the procedure.

Yes.  We have been treating patients from Canada and are open to treating patients from other countries around the world.

We do not require any testing prior to your treatment.  If you wish to have a MRV performed, one can be obtained from any location that offers it near you.  If you wish to have a doppler ultrasound you may contact our offices for a referral to a local ultrasonographer.

Yes.  If you are able to, please send a copy of your CD and report to our office address 3075 Governor’s Place Blvd Suite #120, Dayton, OH 45409, Attn: CCSVI Patient Coordinator.

The procedure includes the venographic evaluation of the jugular and azygos veins (Zamboni protocol).  Treatment typically involves venoplasty of the jugular veins and the azygos vein.

No.  Unfortunately there is no FDA-approved venous stent available on the market.

The use of drug-eluding stents and balloons have been in practice for many years for a variety of indications.  However, in CCSVI, the cause of blockages inside the vein is completely different from heart disease and other artery diseases.  The proper treatment of vein blockages in CCSVI is to dilate the valve open which causes a permanent fix of the blockage.  The use of drug-eluting devices is contradictory to the etiology of the disease process in CCSVI and is thus, completely useless.

To help prevent blood clots from forming inside of the veins after the procedure, all of our patients are placed on a regimen of an anticoagulant and blood thinner after the procedure.  After the procedure you may start taking the anticoagulant for 6 weeks, once you have finished the anticoagulant you may start taking the blood thinner for 6 weeks. Both medications may be offered in coordination with your primary care physician.

3 days, arriving one day before your procedure and leaving the day of your follow-up unless prompted otherwise.

Your procedure is performed on an outpatient basis.  This means that you will check-in in the morning, have the procedure, and be allowed to leave our center after the procedure and after you meet our discharge criteria.

We perform all of our procedures at our medical center in Dayton, OH.

The vascular center where we provide CCSVI treatments has been used by our group since 2006, specifically for endovascular procedures.  These centers have been designed and built to specialize in venograms, angiograms, intravascular ultrasound, atherectomies, angioplasties and stenting.  Our centers are not required to have a designated accreditation like hospitals so there is no formal ‘certificate’ or ‘accreditation’.

As a private group specializing in a wide range of treatments and diseases, we have active privileges at several area hospitals.  We provide both inpatient and outpatient services at these hospitals on a daily basis.  Of note, we have an experienced fulltime ICU trained nurse and Certified Registered Nurse Anesthetist at our facility.

No formal follow-up testing is required.  Additional visits and ultrasounds are optional.

At this time we are following patients based on their response to treatment.  Specifically, if a patient improves after the procedure, and then loses those improvements months later, we would discuss your options with you at that time.

Our fee includes the hotel stay while in Ohio, the consultation prior to your procedure, the procedure itself, and the follow up visit with our physician the day after the procedure.  The procedure includes all nursing, medications, anesthesia, materials (not including stents), recovery time, and facility charges.  Costs not included in the procedure are travel and the medications.  There are no other hidden costs!

The local pharmacy located near our office charges approximately $400.00 USD for the anticoagulant and approximately $30.00 USD for the blood thinner.

No.  The procedure is considered experimental for CCSVI or MS as the indication.

We accept certified checks or all major credit cards as payment for the procedure.  Patients wishing to use a credit card may contact their credit card company to obtain a cash advance for a check.  All payments must be in US Dollars to be accepted by our office.  Payment can be made out to: Dayton Interventional Radiology.

Yes.  You can withdraw money from your HSA and use that money for a certified check.

We have been involved with CCSVI patients since December 2011.  We are the first group to treat CCSVI patients in Ohio and neighboring states.

Each of the physicians at Dayton Interventional Radiology have been treating central venous occlusive disease for years, long before the discovery of CCSVI.  Our physician has performed thousands of central venograms and angioplasties for blocked veins for a variety of different diseases and hundreds of CCSVI procedures.  This extensive experience helps allow us to be a leader in the treatment of CCSVI.

Yes.  Our physician is Board Certified in his respective fields (Neuroradiology and Interventional Radiology).  In addition, since Dayton Interventional Radiology specializes in the treatment of pain, he is also Board Certified by the American Society of Interventional Pain Physicians.

Yes.  Our physician has completed a fellowship in Neuroradiology and Interventional Radiology.  Since neuroradiologic and interventional techniques are the ones used in the treatment of CCSVI patients, we feel fellowship training is very important to ensuring expert care for our patients.

Yes.  We perform venograms on both of the jugular veins and the azygos vein to check for any blockages just as Dr. Zamboni did in his study.  We then treat any abnormalities that we find just as Dr. Zamboni has done.  Our physician has personally discussed this procedure with Dr. Zamboni on 2 separate occasions.  In addition, we also use intravascular ultrasound to obtain highly accurate 3 dimensional visualization of the inside of the vein prior to and after treatment.

The procedures which we are performing on patients (venogram and angioplasty) have been in use for many decades.  Endovenous angioplasty are established and safe techniques in their application to the venous obstructions seen in the jugular and azygos veins.  These procedures are therefore not experimental for indications other than CCSVI.  We do not know if treating these types of blockages will have assured benefits for patients with MS.  Symptoms such as fatigue, headache, insomnia, impaired cognition (brain fog) and vision, disturbed balance, heat intolerance, numbness, stiffness, tremors, weakness, urinary and bowel disturbances, etc. are often present in patients with blockages of the jugular or azygos veins and improvements in the symptoms may be seen post-procedure.

For more information, please call (937) 424-2580

The FDA has issued a general warning for “potential dangers of unproven treatment for multiple sclerosis” and specifically the procedures related to studies with balloon angioplasty devices or stents. We wanted to forward you the link to the FDA website, below, for awareness.